2017.2.21News Releases AMED and NIAID implemented the first international collaboration call and 13 R&D projects were awarded to grant


The Japan Agency for Medical Research and Development (AMED), who’s President is Dr. Makoto Suematu and the National Institute of Allergy and Infectious Diseases (NIAID) of the U.S. National Institutes of Health, who’s Director is Dr. Anthony Fauci, recently identified thirteen outstanding R&D projects submitted in response to a call for international collaborative applications focused on infectious diseases and immunology research.  This call was issued as part of the U.S.-Japan Cooperative Medical Sciences Program and provided a particular opportunity for early-career and female investigators.  Nearly 30 applications were submitted and reviewed by joint Japanese-U.S. panels of expert scientists.  It was the first case for AMED to conduct the entire process of a joint research call and review in English. The result of the call was announced at the 19th International Conference on Emerging Infectious Diseases in the Pacific Rim, which was held jointly by NIH and AMED in collaboration with the local host agency, the International Vaccine Institute (IVI), from February 7th to 10th, 2017, in Seoul, Korea.


This joint research call was implemented between AMED and NIAID to enhance especially, the research capacity of female and early-career investigators, through international collaborative research on infectious diseases spreading in Asian countries, under the U.S. - Japan Cooperative Medical Sciences Program. Joint research applications were prepared and submitted in English with an evaluation criteria being the inclusion of early-stage and/or female researchers in any of the following team combinations; Japan - U.S., Japan - U.S. - Asia, or U.S. - Asia. An international non-governmental organization located in the United States, CRDF Global, helped manage the whole process of the joint call.

To review bacterial, parasitic and virus disease applications three peer review panels were constituted with equal membership of U.S. and Japanese scientists. These panels reviewed 29 applications and identified 13 that were highly meritorious. The three review panels; focused on Viral, Bacterial and Parasitic Diseases, conducted their reviews in English, spending 2 to 3 hours on the review of each application. Utilizing the results of the review, AMED, NIAID and CRDF Global decided to fund all 13 of the highly meritorious applications.  (See the attached list of the awarded projects) and AMED concluded contracts with 10 Japanese sub teams among 13 awarded projects.

Since there is a 14 hour time difference between the United States (Eastern Standard Time) and Japan, and the reviewers were scattered nationwide within the United States, a web and tele-conference system was utilized for implementing the review panels.

This project is a joint research program that AMED and NIH are conducting for the first time after concluding a memorandum of understanding on cooperation in 2015 and it is the first case of an international joint call and joint review in English for AMED. AMED highly promotes the implementation of international collaborative research, and will put more effort into strengthening collaborative research calls and peer review in English.




Japan Agency for Medical Research and Development (AMED)
Division of International Collaboration, Department of International Affairs
Tel: +81-3-6870-2215
E-mail:nichibei"at", Replace "at" with "@". 

List of Awardees

ProjectPrincipal InvestigatorAffiliationCountry
Automated detection of outbreaks of antimicrobial-resistant bacteria in Japan Yahara, Koji  National Institute of Infectious Diseases Japan
Stelling, John Brigham and Women's Hospital U.S.
Dried Blood Spots for Cholera Serosurveillance Diep, Tai The Pasteur Institute, Ho Chi Min City Vietnam
Leung, Daniel University of Utah U.S.
Engineering bacteriocins for therapeutic development targeting pathogenic Enterobacteriaceae Dirphat, Pornphan Mahidol University Thailand
Dziejman, Michelle University of Rochester Medical Center U.S.
Molecular Surveillance of Ceftazidime (CAZ) Resistance in Melioidosis Nakajima, Chie Hokkaido University Japan
Tuanyok, Apichai University of Florida U.S.
Defined antigens for a diagnostic antigen detection test of visceral leishmaniasis Goto, Yasuyuki University of Tokyo Japan
Duthie, Malcolm Infectious Disease Research Institute U.S.
Discovery and molecular understanding of virulence-associated genetic markers of amebiasis Tsukui, Kumiko National Institute of Infectious Diseases Japan
Marie, Chelsea University of Virginia U.S.
Establishment of a novel in vitro system to assess Plasmodium vivax hypnozoites and its application for the metabolomic and pharmacological analysis Kaneko, Osamu Nagasaki University Japan
Patrapuvich, Rapatbhorn Mahidol University Thailand
Rathod, Pradipsinh University of Washington U.S.
Evaluation of P. falciparum/P. vivax protein microarray for detection of subclinical P. falciparum infection and exposure in Myanmar. Han, Kay Thwe Department of Medical Research, Ministry of Health Myanmar
Nyunt, Myaing University of Maryland, Baltimore U.S.
In vitro and in vivo characterization of host factor candidates targeting liver-stage malaria Yamamoto, Masahiro Osaka University Japan
Jacobs-Lorena, Marcelo Johns Hopkins University U.S.
Investigate the gain of immune function after hepatitis C virus eradication from patients Kanda, Tatsuo Chiba University Japan
Ray, Ranjit Saint. Louis University U.S.
Molecular characterization of interferon- resistant HIV-1 using novel imaging techniques Shioda, Tatsuo Osaka University Japan
Hope, Thomas Northwestern University U.S.
Molecular mechanisms by which HIV-1 acquires resistance to second-generation integrase strand transfer inhibitors Hachiya, Atsuko National Hospital Organization Nagoya Center Japan
Kirby, Karen University of Missouri U.S.
The balancing act: hepatic innate immune defense and viral evasion. Aly Ibarhim, Hussein National Institute of Infectious Diseases Japan
Saito, Takeshi University of Southern California U.S.

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Last updated 2017.2.21