Research and Development Projects Adopted in FY2015

Development of manufacturing technology on small bispecific antibody for next generation biologics

<Project Leader>
Asano Ryutaro
Tokyo University of Agriculture and Technology
Development of the technology for synthesizing VHH antibodies with high affinity and stability based on a novel repertoire of genetically encoded amino acids

<Project Leader>
Sakamoto Kensaku
RIKEN Center for Life Science Technologies
Development of a novel muscle-directed DDS for peptide-conjugated morpholino

<Project Leader>
Okada Takashi
Nippon Medical School
Development of siRNA conjugates with tissue-specific delivery functions

<Project Leader>
Ueno Yoshihito
Gifu University
Development of a glycosylation analysis and control system to manufacture functionalized glycoprotein products

<Project Leader>
Kawasaki Nana
Yokohama City University
Development of novel technologies for multi-modal imaging and quantification of bioactive pharmaceuticals

<Project Leader>
Watanabe Yasuyoshi
Center for Life Science Technologies, RIKEN
Spatiotemporal visualization of biopharmaceuticals by whole-body/-organ imaging with single cell resolution

<Project Leader>
Ueda Hiroki
The University of Tokyo
Development of core technology for therapeutic xeno nucleic acid aptamers

<Project Leader>
Kuwahara Masayasu
Nihon University
Development of the methods for high-performance isolation of T-cell receptor (TCR) like antibodies against intracellularly expressing tumor antigens

<Project Leader>
Isobe Masaharu
University of Toyama