Research and Development Projects Adopted in FY2014
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Acceleration of the development for the next generation bio-drugs based on macrocyclic nonstandard peptides
<Project Leader>
Suga Hiroaki
The University of Tokyo -
Structure-based innovation of genome-editing tool (CRISPR) system and its medical application
<Project Leader>
Nureki Osamu
The University of Tokyo -
Development of third generation DNA/RNA heteroduplex oligonucleotide
<Project Leader>
Yokota Takanori
Tokyo Medical and Dental University -
Building a platform for innovative non-toxic oligonucleotide therapeutics
–Synthesis, screening, and evaluation of dual-modified artificial nucleic acids–<Project Leader>
Obika Satoshi
Osaka University -
Development of innovative polyamides that control gene expression on-demand
<Project Leader>
Sugiyama Hiroshi
Kyoto University -
Development of a series of advanced functional antibody drugs using techniques of specific modification to human IgG antibody
<Project Leader>
Ito Yuji
Kagoshima University -
Manipulation of cell fate by multi-functional bio-molecules.
<Project Leader>
Okazaki Taku
The University of Tokushima -
Development of innovative nucleic acids delivery systems based on polymer nanotechnology
<Project Leader>
Nishiyama Nobuhiro
Tokyo Institute of Technology -
Generation of transchromosomic rats that express human antibodies via chromosome engineering technology
<Project Leader>
Kazuki Yasuhiro
Tottori University -
Development of innovative next generation cancer-specific monoclonal antibodies and clinical application
<Project Leader>
Kato Yukinari
Tohoku University -
Technology development for obtaining functional and cancer-specific single-domain antigen receptor complex.
<Project Leader>
Ishikawa Shumpei
The University of Tokyo -
Deployment type nanosheets creation technology development for biopharmaceutical local sustained release
<Project Leader>
Abe Toshiaki
Tohoku University -
Development of a novel drug delivery system using engineered exosomes
<Project Leader>
Yoshioka Yusuke
National Cancer Center -
Establishing innovative drug development platform with the novel non coding RNA enhancing protein translation
<Project Leader>
Piero Carninci
RIKEN Center for Life Science Technologies -
Development of an RNA virus vector system that stably expresses RNAi drug in target tissues and pluripotent stem cells
<Project Leader>
Tomonaga Keizo
Kyoto University -
Smart chemobio antibodies design for unmet disease
<Project Leader>
Umetsu Mitsuo
Tohoku University -
Development of next-generation humanized mice for pre-clinical in vivo testing
<Project Leader>
Ishikawa Fumihiko
RIKEN Center for Integrative Medical Science (IMS)