News Releases & Research Results Study develops a method to elicit antibodies protective against various types of influenza ― Application to a universal influenza vaccine is expected ―

2019.8.28News Releases & Research Results

Outline

Results of research and development by a group of Director Yoshimasa Takahashi, Chief Researcher Yu Adachi, and others of the Department of Immunology, the National Institute of Infectious Diseases.

Key points of the study results

  • The team discovered hemagglutinin antibodies (*) that protect against various subtypes of influenza and identified a modified antigen that can more easily elicit such antibodies.
    * Hemagglutinin antibodies (HA antibodies): major protective antigens contained in the current influenza vaccines and are widely used as a protective immunity parameter correlated with the effectiveness of the vaccine.
  • This discovery and identification is expected to help develop a universal influenza vaccine that protects against all influenza type A viruses.

This research and development was conducted with the support of Research Program on Emerging and Re-emerging Infectious Diseases by AMED.

The results of research and development were published on August 28 in Nature Communications.

Article

Last updated 2019.8.28