News Releases & Research Results Study estimates the transmission routes of HIV-1 (AIDS virus) subtype B strains prevalent in Indonesia

News Releases & Research Results

Outline

Results of research by a group of Professor Masanori Kameoka, Assistant Professor Tomohiro Kotaki of the Department of Public Health, Kobe University Graduate School of Health Sciences, Technical Assistant Shuhei Ueda of the Center for Infectious Diseases, Kobe University Graduate School of Medicine, Professor Nasronudin of the Institute of Tropical Disease, University Airlangga (Indonesia), Doctor Kazushi Motomura of the Osaka Institute of Public Health, and others.

Key points of the study results

  • The research group conducted molecular phylogenetic analyses (*) of the HIV-1 subtype B (HIV-1B) prevalent in Indonesia and successfully estimated the transmission times and routes of Indonesian HIV-1B (introduced from Thailand, Europe, and America in the 1970s to 1980s).
    (*) Molecular phylogenetic analysis: analysis to recover the evolutionary history of species, viruses, and genes (phylogeny) using their gene sequences.
  • The study results elucidated a part of the transmission dynamics and global spread of Indonesian HIV-1B.

This research was conducted with the support of Japan Initiative for Global Research Network Program on Infectious Diseases (J-GRID) by AMED at the Kobe-Indonesia Collaborative Research Center established in the Institute of Tropical Disease, University Airlangga.

The results of research were published on September 27 in Scientific Reports, an international academic journal.

Article

Ueda S., et al. Transmission dynamics of HIV-1 subtype B strains in Indonesia, Scientific Reports
DOI: 10.1038/s41598-019-50491-8

2019.9.27

Last updated 2019.9.27