Division of Innovative Research and Development Advanced Research & Development Programs for Medical Innovation（AMED-CREST, PRIME）

[Research and Development Objective] Molecular understanding of the biological phenomena and responses at the early life stages to improve the quality of health and medical care

The goal of this R&D area is to develop a comprehensive understanding of various biological phenomena at the early stage of life (between fertilization and young adulthood) and the effect of environmental factors on the body during that period for better health and medical care in the future.

Over the past decade, we have come to understand that various biological and environmental factors at the early stage of life later affect health and disease. There have also been a series of studies suggesting that these factors could be risk factors for disease during middle-to-late stages of life (from adulthood into old age) and that the risk factors can even be passed on to subsequent generations. Research focusing on the early stages of life is expected to contribute to improved quality of life (QOL) across all stages. To develop an understanding of biological phenomena and responses at the early life stages, this R&D area will bring together and promote interactions between scientists from diverse fields, including basic biology, medical science, agriculture, engineering, and informatics. This R&D area also aims to establish analytical technology platforms to deepen our understanding, develop applications for these technology platforms, and discover new control technology seeds.

2019

Program Supervisor (PS)

 SASAKI Hiroyuki

Distinguished Professor, Medical Institute of Bioregulation, Kyushu University

Program Officer (PO)

 TAKEDA Hiroyuki

Professor, Faculty of Life Sciences, Kyoto Sangyo University

R&D Area Advisors

UMEZAWA Akihiro

Deputy Director, National Center for Child Health and Development

OHTANI Naoko

Professor, Osaka City University Graduate School of Medicine

KANAI Yae

Professor, Keio University School of Medicine

KIMURA Hiroshi

Professor, Department of Life Science and Technology, Institute of Science Tokyo

SUHARA Tetsuya

Deputy Executive Director, National Institute for Quantum Science and Technology

SEHARA Atsuko

Professor Emeritus, Kyoto University

TSUNODA Tatsuhiko

Professor, Graduate School of Science, The University of Tokyo

MATSUMOTO Mitsuru

Professor, Institute for Enzyme Research, Tokushima University

YOSHIKAWA Takeo

Director, Office of the Center Director, RIKEN Center for Brain Science

YOSHIDA Tomokazu

Member of the Managing Board and Senior Executive officer,
Senior Managing Director, CTO, Sysmex Corporation