Division of Innovative Research and Development Step-Type（FORCE）

Step-type (Frontier Outstanding Research for Clinical Empowerment, FORCE) program promotes prospective R&Ds which can lead to large developments, among research accomplishments obtained from terminated AMED-CREST, PRIME and other projects. FORCE program aims to verify correlations between their achievements and target diseases and to validate generated analytical methods, devices, and instruments, by using human clinical samples.

#Purpose 1, Correlations with human diseases:

• Elucidation of correlations between the object of R&Ds (e.g., proteins, genes, metabolites, biological phenomena) and specific diseases, and researches for their potentials toward medical treatments to narrow down target diseases.
• Establishment of novel/improved model systems for target diseases.

#Purpose 2, Analytical methods, devices, and instruments:

• Verification of versatility and effectiveness of analytical methods, devices, and instruments based on experimental results under various conditions including human clinical samples.
• Improvement and optimization of analytical technologies and methods.

OHSHIMA Etsuo

Senior Fellow, Kirin Holdings Co., Ltd.

ODA Yoshiya

Professor, Graduate School of Medicine, The University of Tokyo

KOHNO Takashi

Chief, Division of Genome Biology, National Cancer Center Research Institute

MOTOHASHI Hozumi

Professor, Institute of Development, Aging and Cancer, Tohoku University