Division of International Strategy International Collaborative Research Program for Tackling the NTDs (Neglected Tropical Diseases) Challenges in African countries _terminated project

Terminated Projects

Title of Research and Development Establishment of the model for controlling neglected tropical diseases based on the development of rapid diagnostic methods and risk analysis
Representative institutions Hokkaido University
Principal Investigator SUZUKI Yasuhiko
Foreign representative institutions(Country) The University of Zambia (Republic of Zambia)
Summary of research and development To control neglected tropical diseases in African continent, we will try to complete following items targeting leprosy and human African trypanosomiasis (HAT) as model diseases.
  1. To grasp the actual situation of leprosy and HAT in Zambia
  2. To develop rapid diagnostic methods for leprosy and HAT and implement them at field sites in Zambia
  3. To establish the control measure packages of leprosy and HAT and provide them to Zambia
Title of Research and Development Integrated research program for the control of dengue fever mosquito in Burkina Faso, West Africa
Foreign representative institutions The Jikei University School of Medicine
Principal Investigator KANUKA Hirotaka
Foreign representative institutions(Country) Université de Ouagadougou (Burkina Faso)
Summary of research and development Integrated vector management (IVM) is defined as a rational decision-making process for the optimal use of resources for vector control. Its aim is to improve the efficacy, cost-effectiveness, ecological soundness and sustainability of disease vector control. The framework in our proposal focuses particularly on four key elements for a holistic IVM strategy in Burkina Faso: a) development of rapid diagnosis methods for pathogen and its vector, b) vector surveillance with systematic monitoring of the seasonality and abundance of vector population, c) understanding mechanism related to vector competency and its control by microbe-based paratransgenesis, and d) neuro-ethological analysis of vector behavior in particular host sensing and blood-feeding. These IVM strategies are additional to, and compatible with, conventional measures (such as use of bed nets) and medicinal therapies. Several small research teams (“mobile-unit”) consisting of faculty members, postdocs, graduate students, and/or technicians will be involved in each study element.
Title of Research and Development An innovative continent-wide NTD surveillance network based on simultaneous multiplex assay technology in Africa
Representative institutions Nagasaki University
Principal Investigator KANEKO Satoshi
Foreign representative institutions(Country) Kenya Medical Research Institute (Republic of Kenya)
Summary of research and development This program intends to develop a continent wide NTD surveillance network based on a multiple assay system. During the research period, it will achieve the following objectives:
  1. Development and Optimization of a multiple assay system based on regional characteristics of NTD infections
  2. Development and evaluation of an implementable NTD surveillance system in Africa
  3. Development of a multiplex assay network, human resources capacity development and information sharing related to NTD surveillance
  4. Sharing of information on NTD’s and NTD surveillance in Africa
  5. Design of an NTD information dissemination platform for the international community.
Title of Research and Development  Integrated research to fight against Bruli ulcer and other skin NTDs in West Africa
Representative institutions Teikyo University
Principal Investigator SUZUKI Koichi
Foreign representative institutions(Country) Raoul Follereau Institute(Cote d'Ivoire
Summary of research and development Buruli ulcer (BU) is one of the major skin-related neglected tropical diseases (skin NTDs) with a considerable gap in its disease control. In this project, we partner with Côte d’Ivoire, one of the countries with the highest BU burden in the world to achieve the following research and development goals:
  1. Development of rapid diagnostic tools for BU
  2. Molecular epidemiological study using portable sequencer
  3. System development and enhancement of surveillance for BU and other skin NTDs
  4. Development of patient management package

Contact

Division Name Division of International Strategy, Department of International Strategy
Tel +81-3-6870-2216
E-Mail amed-ntds“at”amed.go.jp
Remarks

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Last updated 05/09/22