Division of International Strategy International Collaborative Research Program: Strategic International Collaborative Research Program (SICORP)

Outline

Key Fields Innovation and Clinical Research Center Project
R&D phase Basic Study, Applied Study, Nonclinical Study/Pre-clinical Study
Contact
Office of International Collaboration, Division of International Strategy, Department of International Strategy
TEL: +81-3-6870-2210
E-mail: sicorp”at”amed.go.jp(Replace “at” with @)

The aim of this program is to contribute solutions to challenges facing world today and to bolster Japan’s scientific and technological capabilities through collaboration with a broad range of countries.

This program provides support for international joint research projects on the basis of equal partnership in countries,regions,and fields of cooperation that have been designated as particularly important by the Ministry of Education,Culture,Sports,Science and Technology(MEXT)on the basis of intergovernmental agreements,in collaboration with funding agencies in the countries concerned.

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Implementing Body

SICORP (Singapore)

Research Area – "Biological and Molecular Determinants of Human Ageing"
The aims are to: 1) strengthen research collaborations between Japan and Singapore within the field of ”Biological and Molecular Determinants of Human Ageing”; and 2) achieve world-class scientific results through the development and use of new and innovative technologies which can address the challenges facing the international community in the area of health research in both countries.
Funding Agency of Singapore Side
Agency for Science, Technology and Research (A*STAR)
Duration: FY2017 - FY2021
Project Title Biological signatures of cardiovascular, musculoskeletal and cognitive ageing in the very old
Country Japan Singapore
PI Dr. ARAI Yasumichi Dr. Woon-Puay Koh
Affiliation Keio University School of Medicine Duke-NUS Medical School
Project Title Effect of aging of the innate immune system on intracellular system network
Country Japan Singapore
PI Dr. FUJIU Katsuhito Dr. Xiaomeng Wang
Affiliation The University of Tokyo Singapore Eye Research Institute (SERI)
Project Title Targeting age-associated white matter lesions
Country Japan Singapore
PI

Dr. IHARA Masafumi

Dr. Peter Tsun-Hon Wong
Affiliation National Cerebral and Cardiovascular Center National University of Singapore

Research Area – "Cell Therapy - a focus on quality, efficacy and safety"
The aims are to: 1) strengthen research collaborations between Japan and Singapore within the field of ”Cell Therapy - a focus on quality, efficacy and safety” ; and 2) achieve world-class scientific results through the development and use of new and innovative technologies which can address the challenges facing the international community in the area of health research in both countries.
Funding Agency of Singapore Side
Agency for Science, Technology and Research (A*STAR)
Duration: FY2019 - FY2022
Project Title Developing a safe and potentially efficacious piggyBac-based CAR-T cell strategy for virus-related cancers
Country Japan Singapore
PI Dr. SAITO Shoji Dr. Timothy Wai Ho Shuen
Affiliation Department of Pediatric, Shinshu University Division of Medical Oncology, National Cancer Centre Singapore
Project Title Large-scale Preparation of Hair Follicle Germs using Hydrogel Printing
Country Japan Singapore
PI Dr. KAGEYAMA Tatsuto Dr. Michinao Hashimoto
Affiliation Kanagawa Institute of Industrial Science and Technology (KISTEC) Singapore University of Technology and Design
Project Title Human stem cell-derived pancreatic beta cells for the treatment of diabetes
Country Japan Singapore
PI

Dr. SHIRAKAWA Jun

Dr. Adrian Kee Keong Teo
Affiliation Laboratory of Diabetes and Metabolic Disorders, Institute for Molecular and Cellular Regulation, Gunma University A*STAR/NUS Medicine, the Institute of Molecular and Cell Biology (IMCB)

SICORP (Spain)

Research Area – "Nanomedicine"
The aims are to:
1) Strengthen research collaborations between Japan and Spain within the field of Nanomedicine;
2) Achieve world-class scientific results through the development and use of new and innovative
technologies which can address the challenges facing the international community in the area of
health research in both countries.
Funding Agency of Spain Side
State Research Agency of Spain (AEI)
Duration: FY2018 - FY2021
Project Title Development of phototherapeutic strategies for amyloid-related diseases enabled by a nanoscale view of amyloid photodamage (AMYLIGHT)
Country Japan Spain
PI Dr. SOHMA Youhei Dr. Cristina Flors
Affiliation Wakayama Medical University IMDEA Nanociencia
Project Title Drug delivery targeting Brain CPT1: a novel nanomedicine-based approach to fight obesity and cancer (COnCorD)
Country Japan Spain
PI Dr. Sabina Quader Dr. Rosalía Rodríguez-Rodríguez
Affiliation Innovation Centre of Nanomedicine (iCONM) Universidad Internacional de Cataluña
Project Title Nano-scaffolding for neuronal migration and regeneration (Nano-ReBrain)
Country Japan Spain
PI Dr. KANEKO Naoko Dr. Vicente Herranz-Pérez
Affiliation Nagoya City University Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED)

SICORP (UK)

Research Area – "Infectious Diseases"
The overarching aim of the UK-Japan collaborative initiative in infectious diseases is to provide bi-lateral support to biomedical and health researchers in the UK and Japan that will allow them to forge lasting collaborations. This initative aims to strengthen existing links or foster new links that add value to research taking place in both countries. This is expected to be achieved by facilitating exchange and catalysing innovative synergy amongst collaborators and is particularly aimed at those who are in the early stages of their careers.
Funding Agency of the UK Side
The UK Medical Research Council(MRC)
Duration: FY2019 - FY2022
Project Title Elucidation of cell-autonomous immunity and host defense against Toxoplasma gondii by interferon-inducible GTPases
Country Japan U.K.
PI Dr. YAMAMOTO Masahiro Dr. Eva-Maria Frickel
Affiliation Research Institute for Microbial Diseases, Osaka University The University of
Birmingham
Project Title Interferon stimulated defences that target Hepatitis B Virus (HBV) and Hepatitis D Virus (HDV)
Country Japan U.K.
PI Dr. WATASHI Koichi Dr. Sam Wilson
Affiliation National Institute of Infectious Diseases MRC University of Glasgow Centre for Virus Research (CVR)
Project Title Dynamic Imaging in Viral Encephalitis Defines Unique Roles for Chemoattractants
Country Japan U.K.
PI Dr. MIYABE Yoshishige Dr. Benedict Michael
Affiliation Nippon Medical School University of Liverpool
Project Title The HDAC6/USP7 axis in enveloped RNA virus infection
Country Japan U.K.
PI Dr. MIYAKE Yasuyuki Dr. Yohei Yamauchi
Affiliation Nagoya University Graduate School of Medicine University of Bristol School of Cellular and Molecular Medicine
Project Title Systematic analysis of persistence mechanisms by high-throughput bar-seq and single cell analyses
Country Japan U.K.
PI Dr. MUTO-FUJITA Ai Dr. Suzie Hingley-Wilson
Affiliation RIKEN University of Surrey
Project Title A cross-sectional approach to identification & interrogation of adaptive & functional mutations affecting CCHFV replication & pathogenicity in humans
Country Japan U.K.
PI Dr. MORITA Kouichi Dr. David Allen
Affiliation Institute of Tropical Medicine, Nagasaki University London School of Hygiene and Tropical Medicine (LSHTM)
Project Title Study of the T cell Response During Cryptococcal Meningitis Using New Tools
Country Japan U.K.
PI Dr. KAWAKAMI Kazuyoshi Dr. Rebecca Drummond
Affiliation Tohoku University Graduate School of Medicine University of Birmingham
Project Title The human T-cell leukaemia virus HTLV-1: transcriptional heterogeneity at the single-cell level
Country Japan U.K.
PI Dr. SATO Yorifumi Dr. Charles Bangham
Affiliation Kumamoto University Imperial College

SICORP (Germany)

Research Area – "Neuroscience - Computational Connectomics"
The aim of the collaborative project is to provide bi-lateral support to biomedical and health researchers in Japan and Germany that will allow them to forge lasting collaborations in the field of neuroscience-computational connectomics.
Funding Agency of German Side
Deutsche Forschungsgemeinschaft e.V (DFG)
Duration: FY2020 - FY2023
Project Title Computational and Physiological Approaches to the Primate Anxiety Connectome
Country Japan Germany
PI Dr. AMEMORI Ken-ichi Prof. Dr. Peter Dayan
Affiliation Kyoto University Max Planck Institute for Biological Cybernetics / University of Tübingen
Project Title The role of dynamic neural functional coupling in spontaneous thought
Country Japan Germany
PI Dr. Mingbo Cai Dr. Nicolas Schuck
Affiliation The University of Tokyo Max Planck Institute for Human Development
 

SICORP (Canada)

Research Area – "Advancing Epigenetic Technologies"
The aim is to support Japan- and Canada-based early career researchers develop fruitful international collaborations in the field of epigenetic mechanisms and technologies.
Funding Agency of Canadian Side
Canadian Institutes of Health Research (CIHR)
Duration: FY2020 - FY2023
Project Title Artificial Intelligence based adaptive and interpretable models for analyzing multi-track epigenomic sequential data
Country Japan Canada
PI Dr. YAMANAKA Soichiro Dr. Ahmed Ashraf
Affiliation The University of Tokyo University of Manitoba
Project Title Single-cell probing of epigenetic memory in immunity
Country Japan Canada
PI Dr. Jay Shin Dr. David Langlais
Affiliation RIKEN McGill University
Project Title Characterization of the integrative epigenetic and epitranscriptomic
landscape of acute myeloid leukemias
Country Japan Canada
PI Dr. YOSHIMI Akihide Dr. Ly Vu
Affiliation National Cancer Center Research Institute Simon Fraser University
 

Results Report

Management and Evaluation Framework

 PS(Program Supervisor)

SUDA Toshio, M.D., Ph.D., Director and Professor, International Research Center for Medical Sciences, Kumamoto University / Professor, Cancer Science Institute, National University of Singapore

PO(Program Officer)

SICORP (Singapore)

Research Area - "Biological and Molecular Determinants of Human Ageing"

AKISHITA Masahiro, M.D., Ph.D., Professor, Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo / Vice Director, Institute of Gerontology, The University of Tokyo / Vice Director, The University of Tokyo Hospital

Research Area - "Cell Therapy - a fucus on quality, efficacy and safety"

SHIKU Hiroshi, M.D., Ph.D., Professor, Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine

 SICORP (Spain)

HANDA Hiroshi, M.D., Ph.D., Professor, Department of Nanoparticle Translational Research, Tokyo Medical University

 SICORP (UK)

SATO Hironori, M.D., Ph.D., Chief, Pathogen Genomics Center, The National Institute of Infectious Diseases

 SICORP (Germany)

ISA Tadashi, M.D., Ph.D., Professor of Neuroscience, Graduate School of Medicine, Kyoto University

 SICORP (Canada)

USHIJIMA Toshikazu, M.D., Ph.D., Chief, Division of Epigenomic, National Cancer Center Research Institute

Brochure

Last updated 2021.4.1