GA4GH GEM Japan (GEnome Medicine Alliance Japan)
The Global Alliance for Genomics and Health (GA4GH ) is an international organization aiming to advance medical care and medicine through responsible sharing of genomic and health-related data.
The GEM Japan (GEnome Medicine Alliance Japan) has been designated as a GA4GH Driver Project , pursuing integration of the results of AMED projects to realize genomic medicine in Japan.
Michael Baudis, Swiss Personalized Health Network, visited AMED to have an in-person meeting with Japanese Data Scientists
AMED held the GEM Japan Workshop titled Global Career Advancement of Genome and Health Data Scientists
News Release & Research Results
Germline pathogenic variants in 7,636 Japanese patients with prostate cancer and 12,366 controls
GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture
The GEM Japan project, which has covered Program for an Integrated Database of Clinical and Genomic Information, Platform Program for Promotion of Genome Medicine, BioBank Japan Project for Genomic and Clinical Research, Tohoku Medical Megabank Project in Japan, plans to share the allele frequencies as well as disease variations of Japanese population, and has held GEM Japan workshops in order to localize the GA4GH tools into non-English speaking countries.
- TogoVar (Integrated database of Japanese genomic variation) : A database that has collected and organized genome sequence differences between individuals (variants), which has been developed as a joint research project of National Bioscience Database Center (NBDC), JST, and Database Center for Life Science (DBCLS), ROIS.
- MGeND(Medical Genomics Japan Variant Database) : A database aiming to provide the integrated information of genomic variations and clinical characteristics, which has been developed by the AMED program for an Integrated Database of Clinical and Genomic Information.
- BBJ(BioBank Japan) : One of the three major biobanks in Japan managed by the AMED BioBank Japan Project for Genomic and Clinical Research.It has collected DNA, serum and clinical information from more than 270,000 patients nationwide, and thus is regarded as one of the largest disease biobanks in the world.
- TMM (Tohoku Medical Megabank Project) : The project conducts a long-term health study of a total of 150,000 residents living in communities which suffered major damage from the Great East Japan Earthquake and reports the findings to the respective residents with their personal information. It also establishes a system of dispatching physicians on a rotation basis to health care providers in the region.
SUEMATSU Makoto, M.D., Ph.D.
NAKAGAWA Hidewaki, M.D., Ph.D.
AMED Program Officer
Team Leader, Laboratory for Cancer Genomics, RIKEN Center for Integrative Medical Sciences
KOSAKI Kenjiro, M.D., Ph.D.
AMED Program Officer
Professor and Director, Center for Medical Genetics, Keio University School of Medicine
Japan Agency for Medical Research and Development (AMED)
GEM Japan Contact Office
Last updated 2019.11.12