公募情報 令和7年度 「医療分野国際科学技術共同研究開発推進事業（先端国際共同研究推進プログラム（ASPIRE））」に係る公募（第7回）（日・スイス共同研究公募）について

世界最高水準の医療の提供に資する細胞構造・ダイナミクス研究
世界最高水準の医療の提供に資する細胞・臓器・個体間相互作用研究
世界最高水準の医療の提供に資するライフステージ研究

本公募では、炎症老化として知られる加齢に伴う慢性的で低度の炎症の根本的な原因と生物学的機序の研究に焦点を当てます。細胞、分子、全身的要因がどのように炎症老化に関与しているかについての理解を深め、加齢関連疾患への影響を緩和する標的介入を開発することを目的とします。国際共同研究を通じて、高齢化した人々の健康寿命と生活の質を改善するための新しい治療経路を明らかにすることを目指します。
（以下、英語原文）

Call Topic: Mechanisms and Modulation of Inflammaging

This AMED-SNSF joint call focuses on investigating the causes and biological mechanisms of chronic, low-grade inflammation associated with ageing, commonly referred to as “inflammaging”. The collaboration seeks to elucidate how cellular, molecular and systemic factors contribute to inflammaging and to develop targeted interventions to mitigate its impact on age-related diseases. By fostering interdisciplinary collaborations, the project aims to identify novel therapeutic pathways to enhance healthy life expectancy and improve the quality of life of ageing populations.
This joint call is open to all areas of basic research and scientific fields involved in the investigation of inflammaging-related health research. It aims to support cutting-edge research projects that address challenges in inflammaging-related health research, with the goal of expanding our understanding of the biological mechanisms underlying inflammaging.
The call seeks to bridge cellular and molecular research with systemic health outcomes. The collaboration encourages comprehensive approaches to alleviating inflammaging by targeting specific pathways, including miRNA regulation, inflammasome activation, immune cell ageing and gut microbiota modulation. These approaches are expected to provide valuable insights into managing chronic inflammation to prevent or delay the onset of multiple age-related diseases, thereby improving life expectancy and quality of life.

応募資格者

応募資格の詳細は、”Japan-Switzerland AMED-SNSF ASPIRE Joint-Call for Proposals“ の “3.1 Teams’ eligibility” 及び「日本側研究者向け補足応募注意事項」の「第3章　応募要領」をご覧ください。